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doi: 10.1016/j.bmc.2014.05.008 [DOI] [PubMed] [Google Scholar] 89

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Importantly, prospective analyses have shown that non-survivors of burn and SII exhibit markedly reduced levels of key immuno-modulators in BALF, including C5a, IL-1β, and IL-8, indicating that early pulmonary immune hyporesponsiveness is associated with increased mortality risk