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Unlocking the Interactions Between the Whole-Body Microbiome and HPV Infection: A Literature Review
Thus, modulation of various mammalian-specific processes, which do not exist in unicellular amoebae, by Legionella may be an accidental host response to amoebae-adapted effectors, such as the LamA effector that interferes with amoebae encystation but once injected into human macrophages, it triggers a paradoxical pro-inflammatory response
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IL-22-mediated regulation of CXCR2 + neutrophils is a crucial pathogenic pathway in UC, suggesting that the core chemokine module is conserved in colitis development, possibly through signal transducer and activator of transcription 3 (STAT3) signaling [94]
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