l-carnitine mitochondria Function of carnitine in the transport of mitochondrial long-chain Anti-age

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However, when there is an excessive amount of iron in the retina, it will lead to the excessive generation of lipid ROS and an increase in superoxide radicals, which will induce the death of RGCs ( Figure 3 4 Ferroptosis in ocular surface disease 4.1 Ferroptosis and corneal injury The cornea, a transparent avascular tissue at the ocular anterior segment, relies on tight epithelial junctions and redox homeostasis to maintain its refractive and protective functions ( Corneal alkali burns, characterized by saponification of cell membranes and limbal stem cell damage, represent a severe form of injury that disrupts iron metabolism and triggers ferroptosis in corneal epithelial cells (CECs) ( − activity and GPX4 expression, thereby reducing glutamate-induced oxidative stress ( Nishant et al

Anti-age

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Morel & Price, 2003)