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[DOI] [PubMed] [Google Scholar] 117.Bruin GJM, van Asten AC, Xu X, Poppe H

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And I think when we look at drug development pipelines, about 50% of preclinical failures, so that would be something that's tested in an animal that works and then fails in a human clinical drug trial, 50% of those failures can be attributed to poorly selected animal models