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The extent of gonadotoxicity is influenced by several factors, including the specific drug, its dosage, frequency of administration, the type of malignancy being treated, and the concurrent use of other medications such as immunosuppressants
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There is a large population of MCs in the GI tract [233], where they play a fundamental role in maintaining the intestinal barrier by regulating epithelial function and integrity, managing the defensive and immunoregulatory function, modulating both innate and adaptive mucosal immunity, and maintaining neuro-immune interactions [233]
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