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Although still largely unclear, the cause of HT is related to a combination of genetic susceptibility and environmental factors that together provoke the loss of immunological tolerance, with a consequent autoimmune attack on thyroid tissue [3]

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Mitofusin-2 (Mfn2) 65,66,67 and Bcl-2-like protein 1 (Bcl2l1) 68 mRNA levels did not increase in Nlrp3 −/− cells