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When this happens, and additionally infection by SARS-CoV-2 downregulates ACE2 abundance on cell surfaces, as suggested by evidence from related coronaviruses [2], the result is the toxic overaccumulation of ANGII, exacerbated inflammation and, finally, acute respiratory distress syndrome and fulminant myocarditis (Figure 1)

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Ferroptosis in therapy of glioma Drug resistance and the ability to evade cell death are key features of GBM malignancy, resulting in a high rate of disease recurrence and low survival rates for patients