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A double-edged sword: ROS related therapies in the treatment of psoriasis - ScienceDirect
These compounds increase Mn-SOD expression via extracellular-signal-regulated kinase (ERK) activation in HepG2 cells [148]
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This cytokine carries out the following activities: It attracts fibroblasts to the site and promotes their proliferation and transformation into myofibroblasts, promotes collagen production and deposition, acts as a recruiter for osteoblasts and promotes calcification and ossification of the PD plaque, promotes the production of TIMP-1, and promotes the production of MMP-2, which has elastase activity [21,22]
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