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Meanwhile, another study also confirmed that the intervention of donepezil combination therapy reduced doxorubicin-induced neuroinflammation and cerebral oxidative stress as well as restored mitochondrial homeostasis without altering the anticancer properties of doxorubicin in the breast cancer phenotype [167]
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Homocysteine mediated extended lipid peroxidation and production of free radicals species results in acute endothelial disorder and inflammation, similarly accelerating atherosclerotic methods persuading cardiovascular problems
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