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FOXO4-DRI | FOXO4/p53 Interaction Blocker | MedChemExpress

Other experimental models of inflammation employing mice are the demonstration of the anti-inflammatory potential of sulforaphane in lung diseases using cigarette smoke-induced alveolar damage [66], cigarette smoke-exposed asthmatic mice [170], bleomycin-induced pulmonary fibrosis [171], ovalbumin (OVA)-sensitised and cigarette smoke-induced airway inflammation [172], chlorine-induced airway hyper-responsiveness [173], haemorrhagic shock-induced lung injury [174], OVA-induced chronic allergic airways [175], lipopolysaccharide (LPS)-induced acute lung injury [176], respiratory syncytial virus (RSV)-induced bronchopulmonary inflammation [177], and the pulmonary arterial hypertension model [178]

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In our original development discussed above, molecules from the Novartis and Baltruschat sets appeared in both the training and testing sets, and our sets had to be redesigned (Table 1, entries 3–6)