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More recently, connective tissue-based mechanisms have gained increasing attention, suggesting that acupuncture may induce mechanical signals in the extracellular matrix and engage resident cells such as fibroblasts (Yunshan L et al., 2025
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In contrast, LCACs are thought to have the potential to activate inflammation, activating the NF-κB luciferase reporter gene in RAW 264.7 cells in an acyl chain length- and concentration-dependent manner, as well as the phosphorylation of JNK and ERK [54, 55]
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