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Critically, IL-6 concentration is positively correlated with endothelial cell secretion of proinflammatory chemokines IL-8 and MCP-1 and IL-6 signaling in endothelial cells supports neutrophil transmigration (21, 22), suggesting concentration-dependent effects of IL-6 on neutrophil function could be indirectly mediated by the vascular endothelium
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[DOI] [PMC free article] [PubMed] [Google Scholar] 330.Pogson J.H., Ivatt R.M., Sanchez-Martinez A., Tufi R., Wilson E., Mortiboys H., Whitworth A.J
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