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Risk factors include conditions associated with hypoventilation, such as postoperative status, obstructive sleep apnea, obesity, severe pulmonary disease, neuromuscular disease, and concomitant use of other medications that cause respiratory depression.[see WARNINGS] • As with adults, when prescribing codeine for adolescents, healthcare providers should choose the lowest effective dose for the shortest period of time and inform patients and caregivers about these risks and the signs of morphine overdose [see OVERDOSAGE]

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These may include: Fatigue Brain fog Memory loss Neurological problems Heart palpitations Pale skin Muscle weakness Mood changes Appetite loss Constipation Infertility Side Effects of Vitamin B12 While the recommended daily amount of vitamin B12 for adults is 2.4 micrograms, higher doses have been found to be safe