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5E, F), suggesting that MIM-dependent EVs carrying Cas12f are taken up in a CIP4-dependent manner, similar to those carrying Rac1
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The resulting TLR2-TLR1 or TLR2-TLR6 heterodimers recognize tri- or diacylated lipoproteins, respectively, yet heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum without leading to differential signaling (Fig
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