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The authors noted that possibly the more heavily affected workers experienced exposure before the introduction of stricter industrial environmental controls later in the twentieth century or exposure to older solvents such as trichloroethylene, 1,1,1-trichloroethane, carbon tetrachloride, kerosene, white spirit, and acetone, which were more widely used three or more decades ago and may have played a greater etiologic role

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SAMC also exhibits hepatoprotective activity in vivo , as evidenced by its ability to protect the liver of rats affected by nonalcoholic fatty liver disease against chronic injury through inhibition of apoptosis and enhancement of autophagy