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Hence, we conclude that there is a need for more randomized control trials and until then benefits of statins must be weighed against the risks of cognitive decline on an individual basis.” [Chatterjee S et al 2015 Curr Cardiol Rep 17:4] All statin manufacturer package inserts include the same warning: “There have been rare postmarketing reports of cognitive impairment (e.g., memory loss, forgetfulness, amnesia, memory impairment, confusion) associated with statin use

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Abstract Although approached through many concepts, the pleiotropic healing issue, specifically, maintaining/reestablishing tissue integrity, remains a central challenge in pharmacology, particularly when the process is misdirected or not properly controlled