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,, Erastin induces cell death by inhibiting the cystineβglutamate transporter (system X C β ), a heterodimeric complex of SLC7A11 (xCT) and SLC3A2, which results in depletion of intracellular GSH by restricting cysteine availability (Figure 1)
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78,79 Because D-dimer is higher in atrial fibrillation patients with such additional risk factors for stroke as hypertension, diabetes or heart failure, its measurement has been proposed as a biomarker for predicting the risk of stroke
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