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Side Effects and Safety Concerns CJC-1295/Ipamorelin Side Effects Common (experienced by many users): Injection site reactions: redness, mild swelling, occasional bruising Water retention, particularly in the first 2-4 weeks Transient numbness or tingling in hands (carpal tunnel-like symptoms) Headaches, usually mild and temporary Flushing or warmth, especially immediately after injection Less common: Increased hunger (mild compared to MK-677) Lightheadedness or dizziness Joint discomfort (usually transient, may be related to fluid retention) Metabolic effects: Research on growth hormone-releasing peptides shows modest increases in fasting glucose and insulin levels, though these are generally smaller than with direct GH administration

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Effects of delayed NSAID administration after experimental eccentric contraction injury—A cellular and proteomics study