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glutathione peroxidase activity in liver Peroxidase-Catalase Cooperativity Is Required for Resistance to Hydrogen Peroxide by Mature Rat Oligodendrocytes b_att_prd_Sheet Mask
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The reason for this is its affinity for sirtuin 3 (SIRT3), a mitochondrial nicotinamide adenine dinucleotide (NAD+)-dependent acetylase, which is involved in the deacetylation of two SOD lysine residues (lysine 68 and 122) [106]
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This leads to a downregulation of NF-κB–dependent inflammatory genes, providing a mechanistic basis for resveratrol’s observed reduction of cytokine production in PD models (49)
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