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Also, while overall methylation levels and completeness of methylation of particular promoters are similar in individual humans, there are significant differences in overall and specific methylation levels between different tissue types and between normal cells and cancer cells from the same tissue
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These included characteristics of NS/PCs such as morphology, phenotypic marker expression and terminal neural differentiation capacity, as well as purity (absence of undifferentiated cells), chromosomal normality and absence of genomic mutations associated with reported tumorigenesis risks (Extended Data Table 1 and Extended Data Fig
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