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One theoretical concern with TB-500 and BPC-157 relates to angiogenesis promotion
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A recently-concluded phase 1 clinical trial of a single-ascending dose study of BIIB054 in PD patients and healthy volunteers, reported it was well tolerated at single doses up to 90 mg/kg, had a serum half-life of 28 days, and CSF concentrations achieved in healthy volunteers were 0.2% of those seen in plasma (Brys et al., Active immunization approaches have also been previously studied
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