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In aged C57BL/6J models, the combination would be predicted to show: greater telomere length maintenance than Epitalon alone (because GHK-Cu reduces oxidative telomere damage that is not addressed by TERT alone), and greater SASP reduction than GHK-Cu alone (because Epitalon’s Treg-supporting and lymphoid progenitor biology reduces the senescent cell burden that GHK-Cu modulates the output of)
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