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Interestingly, this improvement in affinity is not apparent in the case of SNRIs employed in the study where the K i values remain unchanged or weaken when substitutions in subsite B are made to improve the identity of dDAT-binding pocket to hNET (Supplementary Fig
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Despite these limitations, CoQ 10 can be considered as an important coadjuvant in the treatment of different diseases, especially in chronic conditions affecting the elderly
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