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These immunostimulatory effects are clinically relevant, as ferroptosis-related gene signatures demonstrate strong predictive value for response to PD-1 blockade in recurrent glioblastoma [169]
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Introduction Alpha-lipoic acid (1,2-dithiolane-3-pentanoic acid, ALA) and its reduced form, dihydrolipoic acid (DHLA, Figure 1), are natural antioxidants that are widely distributed in both plants and animals [1,2]
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