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Minimal Change Disease : In this case, PGHS-inhibition by NSAIDs favours the conversion of AA to leukotriene which eventually activates helper T lymphocytes to infiltrate glomeruli causing podocyte injury leading to minimal change disease (MCD) [175]
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Helper T cells (Th cells) initially exist as Th0 precursors, differentiating into specialized subtypes in response to distinct cytokine cues [33] (Fig
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